Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US6762342

Title:Transgenic mice containing intestinal alkaline phosphatase gene disruptions
Inventors:Allen, Keith D.; Cary, NC, USA
Summary:This invention describes a transgenic mouse resulting from a homozygous disruption in an endogenous intestinal alkaline phosphatase gene. The transgenic mouse thus lacks production of functional intestinal alkaline phosphatase protein and exhibits, relative to a wild-type mouse, abnormal activity level. Such a transgenic mouse is useful as a model for disease and for identifying agents that modulate gene expression and gene function, and as a potential treatment for various disease states and disease conditions.
Abstract:The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an intestinal alkaline phosphatase gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6762342
Application Number:US2001000900708
Date Filed:06/07/2001
Date Published:13/07/2004
Assignee:Deltagen, Inc., San Carlos, CA, USA


 
Copyright © 2007 The Institute for Cellular Medicine  8/12/2020