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Stem Cell Related Patent Number US6776988
| Title: | Vectors for gene mutagenesis and gene discovery | | Inventors: | Zambrowicz, Brian; The Woodlands, TX, USA
Friedrich, Glenn A.; The Woodlands, TX, USA
Lilleberg, Stan; Spring, TX, USA
Sands, Arthur T.; The Woodlands, TX, USA | | Summary: | This invention describes vectors which incorporate a novel 3' gene trap cassette which can be used to efficiently trap and identify previously unknown cellular genes. Vectors incorporating the described 3' gene trap cassette have numerous applications in gene discovery and in the production of mutated cells and animals. A eukaryotic cell comprising a vector is employed, and the precise methods of exon encoding, as well as polyadenylation sequences and mediation, are disclosed. | | Abstract: | Novel vectors are described that incorporate, inter alia, a novel 3' gene trap cassette which can be used to efficiently trap and identify previously unknown cellular genes. Vectors incorporating the described 3' gene trap cassette find particular application in gene discovery and in the production of mutated cells and animals. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6776988 | | Application Number: | US2002000158735 | | Date Filed: | 29/05/2002 | | Date Published: | 17/08/2004 | | Assignee: | Lexicon Genetics Incorporated, The Woodlands, TX, USA |
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