Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6784155

Title:Inhibitor and stimulator of stem cell proliferation and uses thereof
Inventors:Wolpe, Stephen D.; Rockville, MD, USA
Tsyrlova, Irena; Gaithersburg, MD, USA
Summary:Described herein are inhibitors and stimulators of stem cell proliferation. Claims of the invention include methods for the isolation and use of stem cell modulating factors for the regulation of stem cell cycles and for the acceleration of post-chemotherapy peripheral blood cell recovery. Further disclosed are polypeptide amino acid sequences, and methods of contacting hematopoietic cells with a stem cell proliferation stimulating amount of INPROL or an opiate compound, or a combination thereof. Therapeutic applications are included, such as in the treatment of autoimmune diseases, cancer, psoriasis, AIDS, anemia and pain.
Abstract:Disclosed and claimed are methods for the isolation and use of stem cell modulating factors for regulating stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors and stimulators of stem cell proliferation.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6784155
Application Number:US1997000832443
Date Filed:03/04/1997
Date Published:31/08/2004
Assignee:Wellstat Therapeutics Corporation, Gaithersburg, MD, USA


 
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