Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6790939

Title:Anti-PSCA antibodies
Inventors:Reiter, Robert E.; Los Angeles, CA, USA
Witte, Owen N.; Sherman Oaks, CA, USA
Saffran, Douglas C.; Los Angeles, CA, USA
Jakobovits, Aya; Beverly Hills, CA, USA
Summary:This invention introduces a novel Prostate Stem Cell Antigen protein, PSCA, which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors. Therapeutic applications of this cell-surface antigen are provided, such as in the diagnosis and treatment of prostate cancer, in the production of vaccines and in the generation of antibodies for use in assays. This invention represents a continuation of other applications filed by the same assignee and inventors.
Abstract:The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6790939
Application Number:US2001000855632
Date Filed:14/05/2001
Date Published:14/09/2004
Assignee:The Regents of the University of California, Oakland, CA, USA


 
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