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Stem Cell Related Patent Number US6797269
Title: | Mesenchymal stem cells as immunosuppressants | Inventors: | Mosca, Joseph D.; Ellicott City, MD, USA
McIntosh, Kevin R.; Ellicott City, MD, USA | Summary: | Described herein is a method of inhibiting a T-cell response to an antigen. The invention relates to a process of modulating immune responses using antigen-presenting human mesenchymal stem cells to induce specific T-cell anergy. Further disclosed is a method to modulate immune responses using human mesenchymal stem cells as a platform for the expression of molecules which will induce T-cell anergy. | Abstract: | The present invention provides a method to modulate immune responses using antigen presenting human mesenchymal stem cells to induce specific T cell anergy. The present invention also provides a method to modulate immune responses using human mesenchymal stem cells as a platform to express molecules which will induce T cell anergy. | US Patent Website: | Click Here for Full Text of Patent | Title Number: | US6797269 | Application Number: | US1999000267456 | Date Filed: | 12/03/1999 | Date Published: | 28/09/2004 | Assignee: | Osiris Therapeutics, Inc., Baltimore, MD, USA |
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