Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6797269

Title:Mesenchymal stem cells as immunosuppressants
Inventors:Mosca, Joseph D.; Ellicott City, MD, USA
McIntosh, Kevin R.; Ellicott City, MD, USA
Summary:Described herein is a method of inhibiting a T-cell response to an antigen. The invention relates to a process of modulating immune responses using antigen-presenting human mesenchymal stem cells to induce specific T-cell anergy. Further disclosed is a method to modulate immune responses using human mesenchymal stem cells as a platform for the expression of molecules which will induce T-cell anergy.
Abstract:The present invention provides a method to modulate immune responses using antigen presenting human mesenchymal stem cells to induce specific T cell anergy. The present invention also provides a method to modulate immune responses using human mesenchymal stem cells as a platform to express molecules which will induce T cell anergy.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6797269
Application Number:US1999000267456
Date Filed:12/03/1999
Date Published:28/09/2004
Assignee:Osiris Therapeutics, Inc., Baltimore, MD, USA


 
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