Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6808702

Title:Treatment of disorders by implanting stem cells and/or progeny thereof into gastrointestinal organs
Inventors:Pasricha, Pankaj J.; Houston, TX, USA
Micci, Maria A.; Dickinson, TX, USA
Summary:Described herein are methods of implanting stem cells into a gastrointestinal organ to treat gastrointestinal disorders. The invention relates to a method of treating a gastrointestinal disorder that includes implanting stem cells and/or the progeny thereof into a gastrointestinal organ of a subject. Further disclosed are methods of producing enhanced levels of insulin that include implanting stem cells and/or the progeny thereof into the pancreas of a subject. Also described are methods of providing nitric oxide (NO) within the gastrointestinal alimentary tract of a subject suffering from a gastrointestinal disorder associated with lower levels of NO, such that the implanted embryonic neural stem cells produce NO. Therapeutic applications emphasize such implantations into the pancreas for the treatment of diabetes.
Abstract:A method of treating a disorder, typically a gastrointestinal disorder, that includes implanting stem cells and/or progeny thereof into a gastrointestinal organ of a subject. Also, a method of producing enhanced levels of insulin that includes implanting stem cells and/or progeny thereof into the pancreas of a subject.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6808702
Application Number:US2001000834110
Date Filed:12/04/2001
Date Published:26/10/2004
Assignee:Board of Regents, the University of Texas System, Austin, TX, USA


 
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