Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US6812027

Title:Discovery, localization, harvest, and propagation of an FGF2 and BDNF-responsive population of neural and neuronal progenitor cells in the adult human forebrain
Inventors:Goldman, Steven A.; South Salem, NY, USA
Nedergaard, Maiken; South Salem, NY, USA
Summary:Described herein are human neural or neuronal progenitor cells isolated from non-embryonal human brain tissue and committed to the formation of neurons, wherein the neurons express a Hu protein. The invention relates to such cells which have been identified in histological sections of the adult human brain, and methods by which neuronal progenitor cells derived from human brain tissue are localized, characterized, harvested, and propagated. Additional methods are provided for the introduction and expression of genes in the brain. Therapeutic applications are included, such as the treatment of neurological diseases including Parkinson's disease, demyelinating diseases, ischemic conditions and traumatic brain injury.
Abstract:The present invention provides neuronal progenitor cells which have been identified in histological sections of the adult human brain. The present invention also provides methods to localize, characterize, harvest, and propagate neuronal progenitor cells derived from human brain tissue. Additional methods are provided for introducing and expressing genes in the brain.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6812027
Application Number:US1999000271969
Date Filed:18/03/1999
Date Published:02/11/2004
Assignee:Cornell Research Foundation, Inc., Ithaca, NY, USA


 
Copyright © 2007 The Institute for Cellular Medicine  6/13/2021