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Stem Cell Related Patent Number US6815185
| Title: | Methods of creating constructs useful for introducing sequences into embryonic stem cells | | Inventors: | Klein, Robert D.; Palo Alto, CA, USA
Brennan, Thomas J.; South San Francisco, CA, USA | | Summary: | Described herein are novel nucleotide constructs comprised of a sequence encoding a positive selection marker flanked by restriction enzyme sites, resulting in the creation of a single-stranded region. Further disclosed are DNA constructs useful for introducing sequences into and disrupting the function of a gene in a cell, particularly in an embryonic stem cell. | | Abstract: | This invention provides novel nucleotide constructs. Also provided are methods for making DNA constructs useful for introducing sequences into and disrupting the function of a gene in a cell, particularly an embryonic stem cell. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6815185 | | Application Number: | US2001000885816 | | Date Filed: | 19/06/2001 | | Date Published: | 09/11/2004 | | Assignee: | None |
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