|
|
|
Stem Cell Related Patent Number US6830927
| Title: | Common neural progenitor for the CNS and PNS | | Inventors: | Rao, Mahendra S.; Salt Lake City, UT, USA
Mujtaba, Tahmina; Sandy, UT, USA | | Summary: | Described herein is a method of generating mammalian neuroepithelial stem cells and glial restricted precursor cells which are self-renewing and can differentiate into central nervous system cells. The invention relates to a method of generating neural crest stem cells via inducing the neuroepithelial stem cells to differentiate in vitro into neural crest stem cells by replating the cells on laminin, withdrawing mitogens, or adding dorsalizing agents to the growth medium. Further disclosed are methods by which derivatives of the peripheral nervous system can be generated by inducing the neural crest stem cells to differentiate in vitro. | | Abstract: | A method of generating neural crest stem cells involves inducing neuroepithelial stem cells to differentiate in vitro into neural crest stem cells. Differentiation can be induced by replating the cells on laminin, withdrawing mitogens, or adding dorsalizing agents to the growth medium. Derivatives of the peripheral nervous system can be generated by inducing the neural crest stem cells to differentiate in vitro. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6830927 | | Application Number: | US1998000073881 | | Date Filed: | 06/05/1998 | | Date Published: | 14/12/2004 | | Assignee: | University of Utah Research Foundation, Salt Lake City, UT, USA |
|
|
