Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US6833269

Title:Making neural cells for human therapy or drug screening from human embryonic stem cells
Inventors:Carpenter, Melissa K.; Castro Valley, CA, USA
Summary:Described herein is a novel neural progenitor cell population which proliferates in vitro and is obtained by differentiating primate pluripotent stem cells. The invention relates to populations of neural progenitor cells, differentiated neurons, glial cells, and astrocytes which are obtained by culturing the stem cell populations in a cocktail of growth conditions that initiates differentiation and establishes the neural progenitor population. Further described are methods by which the progenitors can be differentiated in culture into a variety of different neural phenotypes, including dopaminergic neurons. Therapeutic applications are included, such as in the reconstitution or supplementation of central nervous system function, and in the generation of large quantities of neural cells for drug screening and in the treatment of neurological disorders.
Abstract:This invention provides populations of neural progenitor cells, differentiated neurons, glial cells, and astrocytes. The populations are obtained by culturing stem cell populations (such as embryonic stem cells) in a cocktail of growth conditions that initiates differentiation, and establishes the neural progenitor population. The progenitors can be further differentiated in culture into a variety of different neural phenotypes, including dopaminergic neurons. The differentiated cell populations or the neural progenitors can be generated in large quantities for use in drug screening and the treatment of neurological disorders.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6833269
Application Number:US2001000872183
Date Filed:31/05/2001
Date Published:21/12/2004
Assignee:Geron Corporation, Menlo Park, CA, USA


 
Copyright © 2007 The Institute for Cellular Medicine  6/18/2021