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Stem Cell Related Patent Number US6841386
| Title: | Modulation of primary stem cell differentiation using an insulin-like growth factor binding protein | | Inventors: | Kraus, Morey; Jefferson, MA, USA
Deng, Hongkui; Framingham, MA, USA
Liu, Liqin; Framingham, MA, USA | | Summary: | Described herein are methods of inhibiting the differentiation of a cultured CD34+CD38?- cell, via modulation of the primary, human hematopoietic progenitor stem cell poopulation in culture. Further described are methods of altering the endogenous activity of an insulin-like growth factor in the cell by contacting the cell with insulin-like growth factor binding protein-3 to inhibit differentiation. Methods and materials are disclosed. | | Abstract: | The present invention features methods of modulating primary stem cell differentiation in culture by altering the endogenous activity of an insulin-like growth factor. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6841386 | | Application Number: | US2001000962026 | | Date Filed: | 24/09/2001 | | Date Published: | 11/01/2005 | | Assignee: | Viacell, Inc., Worcester, MA, USA |
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