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Stem Cell Related Patent Number US6858583
| Title: | Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation | | Inventors: | Tsyrlova, Irena; Gaithersburg, MD, USA
Wolpe, Stephen D.; Rockville, MD, USA | | Summary: | Described herein are inhibitors of stem cell proliferation comprised of hemoglobin chains, and methods for the isolation and uses thereof. The invention relates to alpha chain peptide fragments, and the means by which such fragments are employed in the regulation of abnormal stem cell cycles, and in the acceleration of post-chemotherapy peripheral blood cell recovery. Therapeutic applications are disclosed, such as in the protection of stem cells from antiviral agents, in the treatment of cancer, and in the maintenance of mammalian hematopoietic stem cells ex vivo. | | Abstract: | Disclosed and claimed are methods for the isolation and use of stem cell inhibiting factors for regulating the abnormal stem cell cycle and for accelerating the post-chemotherapy peripheral blood cell recovery. Also disclosed and claimed are the inhibitors of stem cell proliferation. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6858583 | | Application Number: | US2003000463699 | | Date Filed: | 18/06/2003 | | Date Published: | 22/02/2005 | | Assignee: | Wellstat Therapeutics Corporation, Gaithersburg, MD, USA |
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