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Stem Cell Related Patent Number US6881822
| Title: | PSCA: prostate stem cell antigen and uses thereof | | Inventors: | Reiter, Robert E.; Los Angeles, CA, USA
Witte, Owen N.; Sherman Oaks, CA, USA
Raitano, Arthur B.; Los Angeles, CA, USA | | Summary: | Described herein is a novel prostate stem cell antigen (PSCA) protein, and uses thereof. The invention relates to PSCA, which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors. Protein fragments and their amino acid residue sequences are provided, as are therapeutic applications in the diagnosis and treatment of prostate cancer, such as in the production of vaccines or in the generation of antibodies for use in assays. | | Abstract: | The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6881822 | | Application Number: | US2001000855153 | | Date Filed: | 14/05/2001 | | Date Published: | 19/04/2005 | | Assignee: | Agensys, Inc., Santa Monica, CA, USA
The Regents of the University of California, Oakland, CA, USA |
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