Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6881822

Title:PSCA: prostate stem cell antigen and uses thereof
Inventors:Reiter, Robert E.; Los Angeles, CA, USA
Witte, Owen N.; Sherman Oaks, CA, USA
Raitano, Arthur B.; Los Angeles, CA, USA
Summary:Described herein is a novel prostate stem cell antigen (PSCA) protein, and uses thereof. The invention relates to PSCA, which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors. Protein fragments and their amino acid residue sequences are provided, as are therapeutic applications in the diagnosis and treatment of prostate cancer, such as in the production of vaccines or in the generation of antibodies for use in assays.
Abstract:The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6881822
Application Number:US2001000855153
Date Filed:14/05/2001
Date Published:19/04/2005
Assignee:Agensys, Inc., Santa Monica, CA, USA The Regents of the University of California, Oakland, CA, USA


 
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