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Stem Cell Related Patent Number US6890735
| Title: | TSG-like gene | | Inventors: | Kitamura, Toshio; Tokyo, Japan
Morita, Sumiyo; Tokyo, Japan | | Summary: | Described herein is a TSG-like gene and encoded protein, used to study the differentiation of hematopoietic stem cells and mechanism of bone formation. The invention relates to a gene encoding a novel protein that is homologous to Drosophila TSG and was isolated from a cDNA library derived from the AGM region of a mouse embryo by use of an originally developed cloning method specific to a gene encoding a membrane secretory protein. Therapeutic applications of such a gene are included, such as in the development of drugs regulating immune and hematopoietic functions, and in the treatment of bone disease. | | Abstract: | A gene encoding a novel protein that is homologous to Drosophila TSG was isolated from a cDNA library derived from the AGM region of mouse embryos by using an originally developed cloning method specific to a gene encoding a membrane secretory protein. This gene is useful in developing drugs that regulate hematopoietic stem cell generation, immune and hematopoietic functions, etc. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US6890735 | | Application Number: | US2002000092925 | | Date Filed: | 06/03/2002 | | Date Published: | 10/05/2005 | | Assignee: | Chugai Seiyaku Kabushiki Kaisha, Tokyo, Japan
Kitamura, Toshio, Tokyo, Japan |
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