Methods comprising apoptosis inhibitors for the generation of transgenic pigs

Stem Cell Clinic
Patient Application
FAQ
Contact
Locations
News
Videos
Research
Patents
3D Culture/Scaffold
Administration
Differentiation
Expansion
Extraction/Preservation
Mobilization
Type
USE
 


Stem Cell Related Patent Number US6924096

Title:Delivery construct for antisense nucleic acids and methods of use
Inventors:Dietz, Harry C.; Towson, MD, USA
Summary:This invention describes a novel nucleic acid construct for the delivery of antisense targeting sequences, such that the construct includes intact stem loop structures and an antisense nucleic acid itself. Further disclosed are optional methods by which a ribozyme nucleic acid is included in the construct. Therapeutic applications are provided, such as in the suppression and inhibition of selected genes in a cell and in allele-specific targeting in combination with replacement gene therapy.
Abstract:A novel nucleic acid construct for delivery of antisense targeting sequences is provided. The construct includes intact stem loop structures and an antisense nucleic acid. Optionally, a ribozyme nucleic acid is included in the construct. The construct is useful for inhibition of selected genes in a cell. This allele-specific targeting is also useful in combination with replacement gene therapy.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6924096
Application Number:US1998000163289
Date Filed:29/09/1998
Date Published:02/08/2005
Assignee:The Johns Hopkins University School of Medicine, Baltimore, MD, USA


 
Copyright © 2007 The Institute for Cellular Medicine  8/4/2020