Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6936281

Title:Human mesenchymal progenitor cell
Inventors:Seshi, Beerelli; Tampa, FL, USA
Summary:Described herein are isolated and purified pluri-differentiated mesenchymal progenitor cells, methods and uses thereof. The invention relates to isolated pluri-differentiated human mesenchymal progenitor cells (MPCs), a method for isolating and purifying the human mesenchymal progenitor cells from Dexter-type cultures, and characterizations of such cells. Therapeutic and diagnostic applications are provided, such as in the enhancement of human bone marrow or hematopoietic progenitor cell engraftment, and for the treatment of graft-versus-host disease.
Abstract:There is provided an isolated pluri-differentiated human mesenchymal progenitor cells (MPCs), a method for isolating and purifying human mesenchymal progenitor cells from Dexter-type cultures, and characterization of and uses, particularly therapeutic uses for such cells. Specifically, there is provided isolated MPCs which can be used for diagnostic purposes, to enhance the engraftment of hematopoietic progenitor cells, enhance bone marrow transplantation, or aid in the treatment or prevention of graft versus host disease.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6936281
Application Number:US2001000914508
Date Filed:21/05/2001
Date Published:30/08/2005
Assignee:University of South Florida, Tampa, FL, USA


 
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