Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US6991813

Title:Physiological tissue repair and functional organ regeneration by cultivation of regenerative stem cells in vivo and in situ
Inventors:Xu; Rongxiang, Arcadia, CA, USA
Summary:This invention describes a novel composition comprised of a fatty acid-containing oil and a sterol compound, methods and uses thereof. Further disclosed are techniques by which suitable keratinocytes are activated in vivo, as are the means by which a sterol compound is dissolved in the oil at a concentration of at least 0.5% by weight. Therapeutic applications are provided, including pharmaceutical and nutraceutical uses in animals and in humans, such as in the treatment of various conditions caused by injury, disease or aging, including the regeneration of new organs through the cultivation of regenerative stem cells in vivo and in situ. Claims of the invention include applications which have already proven successful, such as in the regeneration of skin with normal physiological structure at a wound site in a mammal.
Abstract:The present invention provides novel compositions and methods for pharmaceutical or nutraceutical use in an animal, preferably in a human. In one aspect, compositions and methods are provided for promoting cell growth, tissue repair and organ regeneration, preferably in vivo and in situ. The composition comprises a sterol compound dissolved in oil at a concentration at least 0.5% by weight. The compositions may be used in the treatment of various conditions caused by injury, diseases and aging. As shown clinically, the methodology disclosed in the present invention was used successfully to regenerate or clone a new organ through cultivation of regenerative stem cells in vivo and in situ.
US Patent Website:Click Here for Full Text of Patent
Title Number:US6991813
Application Number:US2002000187268
Date Filed:28/06/2002
Date Published:31/01/2006
Assignee:Xu; Rongxiang, Arcadia, CA, USA


 
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