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Stem Cell Related Patent Number US7022518
| Title: | Apparatus and method for co-culturing of cells | | Inventors: | Feye, Glen; San Diego, CA, USA | | Summary: | Herein is described a co-culture apparatus for converting a progenitor cell line into a target cell line. The novel apparatus comprises an exterior receptacle, a removable cartridge that fits into the exterior receptacle, and a closure member to seal the apparatus. Further disclosed are methods by which a progenitor cell line is established, followed by the establishment of a support cell line and co-culturing of the progenitor and support cell lines together, after which a transformation cell line is established and co-cultured with the progenitor cell lines, resulting in the transformation cell line supporting the transformation of the progenitor cell line into a target cell line. | | Abstract: | A co-culture apparatus and method for, among other things, converting a progenitor cell line into a target cell line. The apparatus comprises an exterior receptacle, a removable cartridge that fits into the exterior receptacle, and a closure member to seal the apparatus. The invention is also directed to a method for transforming a progenitor cell line into a target cell line. In one embodiment of the invention, the method comprises the steps of: establishing a progenitor cell line; establishing a support cell line; co-culturing said progenitor and support cell lines; establishing a transformation cell line; and co-culturing said progenitor and transformation cell lines, wherein the transformation cell line supports the transformation of the progenitor cell line into a target cell line. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US7022518 | | Application Number: | US2005000045334 | | Date Filed: | 31/01/2005 | | Date Published: | 04/04/2006 | | Assignee: | None |
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