Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US7029695

Title:Therapeutic compositions containing glutathione analogs
Inventors:Redelmeier, Thomas; Vancouver, Canada
Kauvar, Lawrence M.; San Francisco, CA, USA
Lum, Robert T.; Palo Alto, CA, USA
Lyttle, Matthew H.; Point Reyes Station, CA, USA
Macsata, Robert W.; Pleasanton, CA, USA
Schow, Steven R.; Redwood Shores, CA, USA
Villar, Hugo O.; La Jolla, CA, USA
Kozlowski, Michael R.; Poway, CA, USA
Summary:This invention introduces a novel composition containing a glutathione compound which is useful for stimulating and modulating hematopoiesis. The invention relates to lipid formulations of a glutathione analog and methods of manufacturing them as well as their pharmaceutical compositions. Applications are described in the stimulation of hematopoiesis, to protect hematopoietic cells from damage caused by radiation or chemotherapy, and to potentiate the stimulatory action of one or a combination of cytokines in the formation of colonies by hematopoietic progenitor cells. Also included are therapeutic applications in protecting patients from the destructive effects of a chemotherapeutic agent or irradiation.
Abstract:
US Patent Website:Click Here for Full Text of Patent
Title Number:US7029695
Application Number:US2001000903442
Date Filed:10/07/2001
Date Published:18/04/2006
Assignee:Telik, Inc., Palo Alto, CA, USA


 
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