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Stem Cell Related Patent Number US7049072
| Title: | Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state | | Inventors: | Seshi, Beerelli; Torrance, CA, USA | | Summary: | This invention describes the methods and uses of novel pluri-differentiated human mesenchymal progenitor cells (MPCs). A method of isolation and purification is described for Dexter-type cultures, and therapeutic uses are included for enhancing the engraftment of hematopoietic progenitor cells or bone marrow transplantation, or for diagnosing, treating or preventing graft-versus-host disease. Further clinical applications are addressed, particularly in the diagnosis of leukemia. | | Abstract: | Pluri-differentiated human mesenchymal progenitor cells (MPCs) are isolated. A method isolates and purifies human mesenchymal progenitor cells from Dexter-type cultures for characterization of and uses, particularly therapeutic uses for such cells. Specifically, isolated MPCs can be used for diagnostic purposes, to enhance the engraftment of hematopoietic progenitor cells, enhance bone marrow transplantation, or aid in the treatment or prevention of graft versus host disease. | | US Patent Website: | Click Here for Full Text of Patent | | Title Number: | US7049072 | | Application Number: | US2002000263419 | | Date Filed: | 03/10/2002 | | Date Published: | 23/05/2006 | | Assignee: | University of South Florida, Tampa |
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