Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US7049072

Title:Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state
Inventors:Seshi, Beerelli; Torrance, CA, USA
Summary:This invention describes the methods and uses of novel pluri-differentiated human mesenchymal progenitor cells (MPCs). A method of isolation and purification is described for Dexter-type cultures, and therapeutic uses are included for enhancing the engraftment of hematopoietic progenitor cells or bone marrow transplantation, or for diagnosing, treating or preventing graft-versus-host disease. Further clinical applications are addressed, particularly in the diagnosis of leukemia.
Abstract:Pluri-differentiated human mesenchymal progenitor cells (MPCs) are isolated. A method isolates and purifies human mesenchymal progenitor cells from Dexter-type cultures for characterization of and uses, particularly therapeutic uses for such cells. Specifically, isolated MPCs can be used for diagnostic purposes, to enhance the engraftment of hematopoietic progenitor cells, enhance bone marrow transplantation, or aid in the treatment or prevention of graft versus host disease.
US Patent Website:Click Here for Full Text of Patent
Title Number:US7049072
Application Number:US2002000263419
Date Filed:03/10/2002
Date Published:23/05/2006
Assignee:University of South Florida, Tampa


 
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