Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US7067314

Title:Monoclonal antibody, its immunoreactive fragment and hybridoma
Inventors:Ohara, Takaaki; Kobe, Japan
Summary:Described herein is a novel monoclonal antibody which recognizes human immature hemopoietic stem cells but does not recognize CD34+ Jurkat cells. The invention relates to the HSCA-3 antigen occurring in immature hemopoietic stem cells and a monoclonal antibody recognizing the antigen. Further disclosed are methods of immunoassay and flow cytometry involving antibody labeling, and the isolation and purification of immature hemopoietic stem cells from human bone marrow cells, umbilical code blood or blood enriched in human hemopoietic stem cells by mobilization with G-CSF.
Abstract:It is an object to utilize a novel HSCA-3 antigen occurring in immature hemopoietic stem cells and a monoclonal antibody recognizing said antigen in 1) the immunoassay or flow cytometry involving antibody labeling and 2) the isolation and purification of immature hemopoietic stem cells from human bone marrow cells, umbilical code blood or blood enriched in human hemopoietic stem cells by mobilization with G-CSF. It is directed to a novel HSCA-3 antigen occurring in immature hemopoietic stem cells and to a monoclonal antibody or an immunoreactive fragment thereof which recognizes said antigen. [From equivalent US20020197655A1] It is an object to utilize a novel HSCA-3 antigen occurring in immature hemopoietic stem cells and a monoclonal antibody recognizing said antigen in 1) the immunoassay or flow cytometry involving antibody labeling and 2) the isolation and purification of immature hemopoietic stem cells from human bone marrow cells, umbilical code blood or blood enriched in human hemopoietic stem cells by mobilization with G-CSF. It is directed to a novel HSCA-3 antigen occurring in immature hemopoietic stem cells and to a monoclonal antibody or an immunoreactive fragment thereof which recognizes said antigen.
US Patent Website:Click Here for Full Text of Patent
Title Number:US7067314
Application Number:US2002000172986
Date Filed:18/06/2002
Date Published:27/06/2006
Assignee:Kaneka Corporation, Osaka, Japan


 
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