Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US7070759

Title:High dose radionuclide complexes for bone marrow suppression
Inventors:Fritzberg, Alan R.; Olga, WA, USA
Abrams, Paul G.; Seattle, WA, USA
Tatalick, Lauren Marie; Redmond, WA, USA
Thoelke, Kent R.; Seattle, WA, USA
Bryan, James Kyle; Seattle, WA, USA
Hylarides, Mark D.; Stanwood, WA, USA
John, Elizabeth K.; San Diego, CA, USA
Summary:This is a continuation of patent no. US7097823, by the same assignee and inventors. This invention further develops a therapeutic method for treating leukemia, in which hydration of the patient is followed by administration of the radioprotectant, after which the patient receives a stem cell transplant, instead of full body radiation. Specific radioprotectant and stem cell transplantation methods are disclosed.
Abstract:The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
US Patent Website:Click Here for Full Text of Patent
Title Number:US7070759
Application Number:US2005000041828
Date Filed:24/01/2005
Date Published:04/07/2006
Assignee:NeoRx Corporation, Seattle, WA, USA


 
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