Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US7129215

Title:Tripeptide and tetrapeptide thioethers
Inventors:Aurrecoechea, Natalia; Oakland, CA, USA
Kelson, Andrew B.; San Carlos, CA, USA
Macsata, Robert W.; Pleasanton, CA, USA
Robinson, Louise; San Carlos, CA, USA
Sanchez, Anthony J.; Oakland, CA, USA
Santiago, Nicholas M.; San Francisco, CA, USA
Schow, Steven R.; Redwood City, CA, USA
Simon, Reyna J.; Los Gatos, CA, USA
Summary:This invention describes new glutamyl containing tripeptide and tetrapeptide thioethers, as well as relevant pharmaceutical compositions and methods of use thereof. Further disclosed are therapeutic applications in the treatment of cancer, including the means by which such compounds may be used in the potentiation of the selectively cytotoxic effects of chemotherapeutic agents in tumor cells. Also described are treatments involving the elevation of the production of GM progenitors in bone marrow, the stimulation of the differentiation of bone marrow, the mitigation of the myelosuppressive effects of chemotherapeutic agents, and the modulation of hematopoiesis in bone marrow.
Abstract:
US Patent Website:Click Here for Full Text of Patent
Title Number:US7129215
Application Number:US2006000325846
Date Filed:04/01/2006
Date Published:31/10/2006
Assignee:Telik, Inc., Palo Alto, CA, USA


 
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