Methods comprising apoptosis inhibitors for the generation of transgenic pigs

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Stem Cell Related Patent Number US7138275

Title:Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
Inventors:Kremer, Bernd Karl Friedrich; Kiel, Germany
Fändrich, Fred; Kiel, Germany
Ruhnke, Maren née Schulze; Kiel, Germany
Summary:This invention describes a method of producing dedifferentiated, programmable stem cells of human monocytic origin using a culture medium comprised of M-CSF and IL-3. Further described are pharmaceutical preparations containing the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue. The dedifferentiated, programmable cells of human monocytic origin described herein express CD14, CD90 and CD123 antigens and are useful in the treatment of cirrhosis, pancreatic insufficiency, kidney failure, cardiac infarction and stroke
Abstract:The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.
US Patent Website:Click Here for Full Text of Patent
Title Number:US7138275
Application Number:US2003000401026
Date Filed:28/03/2003
Date Published:21/11/2006
Assignee:Blasticon Biotechnologische Forschung GmbH, Keil, Germany


 
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